Publikacje - Instytut Biochemii i Biofizyki Polskiej Akademii Nauk

JARDANOWSKA-KOTUNIAK M., DRAMIŃSKI M., WŁASNOWOLSKI M., ŁAPIŃSKI M., SENGUPTA K., AGARWAL A., GHOSH N., PANCALDI V., GRYNBERG M., SAHA I., PLEWCZYŃSKI D., DĄBROWSKI M.J., Unveiling epigenetic regulatory elements associated with breast cancer development. International Journal of Molecular Sciences (2025) 26(14): 6558 (39 p.) DOI: 10.3390/ijms26146558 IF 4.9 (2024)

GAWRYLAK A., BRODACZEWSKA K., IWANICKA-NOWICKA R., KOBLOWSKA M., SYNOWIEC A., BODNAR L., SZCZYKLIK C., LESYNG B., STEC R., KIEDA C., Hypoxia alters the response of ovarian cancer cells to the mitomycin C drug. Frontiers in Cell and Developmental Biology (2025) 13: 1575134 (15 p.) DOI: 10.3389/fcell.2025.1575134 IF 4.3 (2024)

PASTERNY Z., BARUA D., MANCERA E., MUSZEWSKA A., Analysis of NUDIX enzymes across fungi reveals previously unrecognized diversity. BMC Genomics (2025) 26(1): 606 (17 p.) DOI: 10.1186/s12864-025-11778-5 IF 3.7 (2024)

CZERWIŃSKA P., WIELECHOWSKA M., MILEWSKI Ł., SIEDLECKI P., ŁUKOWSKA-CHOJNACKA E., Pro-apoptotic activity of 1-(4,5,6,7-Tetrabromo-1H-benzimidazol-1-yl) propan-2-one, anintracellular inhibitor of IM-1 kinase in acute lymphoblastic leukemia and breast cancer cells. International Journal of Molecular Sciences (2025) 26(12): 5897 (24 p.) DOI: 10.3390/ijms26125897 IF 4.9 (2024)

BAR A., BERKOWICZ P., KURPIŃSKA A., MOHAISSEN T., KARAŚ A., KACZARA P., SURAJ-PRAŻMOWSKA J., STERNAK M., MARCZYK B., MALINOWSKA A., ET AL. Effects of life‑long hyperlipidaemia on age‑dependent development of endothelial dysfunction in humanised dyslipidaemic mice. GeroScience (2025) 47(3): 2673–2701 DOI: 10.1007/s11357-025-01578-w IF 5.4 (2024)

SACHAROWSKI S., KUBALA S., ĆWIEK P., STECIUK J., GRATKOWSKA-ŻMUDA DOMINIKA M., OKSIŃSKA P., BUCIOR E., ROLICKA A.T., CIEŚLA M., NOWICKA K., ALSEEKH S., TOHGE T., GIAVALISCO P., ZUGAJ D.Ł., STOLZE S.C., HARZEN A., FRANZEN R., HUETTEL B., GRZESIUK E., HAJIREZAEI M-R., NAKAGAMI H., KONCZ C., FERNIE A.R., SARNOWSKI T.J., BAF60/SWP73 subunits define subclasses of SWI/SNF chromatin remodelling complexes in Arabidopsis. New Phytologist (2025) 247(2): 791–812 DOI: 10.1111/nph.70182 IF 8.1 (2024)

ZHAKYPBEK Y., RAKHMETULLINA A., KAMARKHAN Z., TURSBEKOV S., SHI Q., XING F., PYRKOVA A., IVASHCHENKO A., KOSSALBAYEV B.D., BELKOZHAYEV A.M., In silico analysis of miRNA-mRNA binding sites in Arabidopsis thaliana as a model for drought-tolerant plants. Plants (2025) 14(12): 1800 (18 p.) DOI: 10.3390/plants14121800 IF 4.1 (2024)

ALEKSANDRZAK-PIEKARCZYK T., GRZESIAK J., GAWOR J., KOSIOREK K., Genome sequences of polar Carnobacterium maltaromaticum strains 2857 and 2862 with genes for glycerol and 1,2-propanediol pathways. Microbiology Resource Announcements (2025) 14(6): e0028325 (3 p.) DOI: 10.1128/mra.00283-25 IF 0.6 (2024)

STAROS R., FORONCEWICZ B., KAMIŃSKA D., DĘBORSKA-MATERKOWSKA D., ET AL.,PĄCZEK L., MUCHA K., Does the organ matter in PTLD development in solid organ transplant recipients? A multicenter observational study of risk and prognostic factors. Cancers (2025) 17(11): 1770 (14 p.) DOI: 10.3390/cancers17111770 IF 4.4 (2024)

KHANAL S., THAKUR P., SHARMA A., KUMAR A., PILLAI M., KUMAR D., KUMAR A., ET AL. Unlocking the therapeutic potential of bioactive compounds in Ganoderma lucidum: a new frontier in natural medicine. 3 Biotech (2025) 15(7): 203 (21 p.) DOI: 10.1007/s13205-025-04353-y IF 2.9 (2024)

PUCHAŁA W., KISTOWSKI M., ZHUKOVA L., BURDUKIEWICZ M., DADLEZ M., HRaDeX: R package and web server for computing high-resolution deuterium uptake rates for HDX–MS data. Journal of Proteome Research (2025) 24(4): 1688-1700 DOI: 10.1021/acs.jproteome.4c00700 IF 3.6 (2024)

KWIATKOWSKA J., STEIN E., ROMANENKO A., PLENS-GAŁĄSKA M., PODSIADŁA-BIAŁOSKÓRSKA M., SZOŁAJSKA E., KÜHN U., KAMIENIARZ-GDULA K., A beginners guide to Sf9 and Sf21 insect cell line culture and troubleshooting. Scientific Reports (2025) 15(1): 19907 (18 p.) DOI: 10.1038/s41598-025-99812-0 IF 3.9 (2024)

MARHELAVA K., FIDYT K., PEPEK M., KRAWCZYK M., FORCADOS CH., MALINOWSKA A., ŚWIDERSKA B., ET AL. LILRB1-directed CAR-T cells for the treatment of hematological malignancies. Leukemia (2025) 39(6): 1395–1411 DOI: 10.1038/s41375-025-02580-z IF 13.4 (2024)

KAMIŃSKA K., ŚWIDERSKA B., MALINOWSKA A., BARBASZ J., GRZESIAK M., Vitamin D3 and insulin treatment affects porcine follicular fluid-derived extracellular vesicles characteristics and proteome cargo. Reproductive Biology (2025) 25(3): 101040 (16 p.) DOI: 10.1016/j.repbio.2025.101040 IF 2.0 (2024)

MOSZCZUK B., MUCHA K., KUCHARCZYK R., ZAGOŻDŻON R., The role of glomerular and serum expression of lymphocyte activating factors BAFF and APRIL in patient with membranous and IgA nephropathies. Archivum Immunologiae et Therapiae Experimentalis (2025) 73(1): [12 p] DOI: 10.2478/aite-2025-0018 IF 3.9 (2024)

UNRUG-BIELAWSKA K., SANDOWSKA-MARKIEWICZ Z., PYŚNIAK K., PIĄTKOWSKA M., CZARNOWSKI P., GORYCA K., MRÓZ A., ŻEBER-LUBECKA N., WÓJCIK-TRECHCIŃSKA U., BAŁABAS A., DĄBROWSKA M., SURYNT P., RADKIEWICZ M., MIKUŁA M., OSTROWSKI J., Western Diet and fecal microbiota transplantation alter phenotypic, liver fatty acids, and gut metagenomics and metabolomics in Mtarc2 knockout mice. Genes and Nutrition (2025) 20(1): 13 (26 p.) DOI: 10.1186/s12263-025-00772-x IF 4.9 (2024)

ZERBINI F.M., SIMMONDS P., ADRIAENSSENS E.M., LEFKOWITZ E.J., OKSANEN H.M., ALFENAS-ZERBINI P., AYLWARD F.O., FREITAS-ASTÚA J., ŁOBOCKA M., ET AL. Virus species names have been standardized; virus names remain unchanged. mSphere (2025) 10(5): e0002025 (8 p.) DOI: 10.1128/msphere.00020-25 IF 3.1 (2024)

ŁOPUSIŃSKA A., TYS M., BOGUTA M., CIEŚLA M., RNA polymerase III transcription machinery and tRNA processing are regulated by the ubiquitin ligase Rsp5. Biochimica et Biophysica Acta-Molecular Cell Research (2025) 872(6): 119993 (11 p.) DOI: 10.1016/j.bbamcr.2025.119993 IF 3.7 (2024)

KRAWCZYK P.S., MAZUR M., ORZEŁ W., GEWARTOWSKA O., JELEŃ S., ANTCZAK W., KASZTELAN K., BROUZE A., MATYLLA-KULIŃSKA K., GUMIŃSKA N., TARKOWSKI B., OWCZAREK E.P., AFFEK K., TUROWSKI P., TUDEK A., SROKA M., ŚPIEWLA T., ET AL. Re-adenylation by TENT5A enhances efficacy of SARS-CoV-2 mRNA vaccines. Nature (2025) 641(8064): 984-992 DOI: 10.1038/s41586-025-08842-1 IF 48.5 (2024)

BOCHTLER M., Introducing the “other” type of DNA methylation. Science Advances (2025) 11(20): adx6879 (3 p.) DOI: 10.1126/sciadv.adx6879 IF 12.5 (2024)

LINKE V., CHODKOWSKI M., KASZUBA K., RADKIEWICZ K., SCHRADER T.A., DAS H., RANA V., STADNIK D., DADLEZ M., WARSCHEID B., CHACIŃSKA A., Integrated proteome and lipidome analyses place OCIAD1 at the mitochondria–peroxisome intersection balancing lipid metabolism. Journal of Cell Science (2025) 138(9): jcs263729 (21 p.) DOI: 10.1242/jcs.263729 IF 3.6 (2024)

STASIAK-RÓŻAŃSKA L., GAWOR J., PIWOWAREK K.P., FABISZEWSKA A., ALEKSANDRZAK-PIEKARCZYK T., Co-fermentation and genomic insights into Lactic Acid Bacteria for enhanced propionic acid production using a non-GMO approach. Foods (2025) 14(9): 1573 (16 p.) DOI: 10.3390/foods14091573 IF 5.1 (2024)

RAKHMETULLINA A., ŁUKASIK A., ZIELENKIEWICZ P., An overview of miRNA and miRNA target analysis tools. Chapter 2 in: Plant MicroRNAs: Methods and Protocols, Methods in Molecular Biology/ Ed. S. de Folter, Humana Press, 2025, vol. 2900 ; ISBN 978-1-0716-4397-6 [366 p.], p. 43-71 DOI: 10.1007/978-1-0716-4398-3_2

SHUXIA Z., PING Z., XIAOYAN Z., SICHAO M., XINYI X., WALDRON K.,CHENFENG W., ROUBY S.R., GHONAIM A.H. , XINGXIANG CH., FB1 causes barrier damage to vascular endothelial cells through ferroptosis
by a PINK1/Parkin mediated mitophagy-dependent mechanism. Chemico-Biological Interactions (2025) 416: 111536 (13 p.) DOI: 10.1016/j.cbi.2025.111536 IF 5.4 (2024)

SLYVKA A., RATHORE I., YANG R., GEWARTOWSKA O., KANAI T., LOUNTOS G.T., SKOWRONEK K., CZARNOCKI-CIECIURA M., WŁODAWER A., BOCHTLER M., Activity and structure of human (d)CTP deaminase CDADC1. Proceedings of the National Academy of Sciences of the United States of America (2025) 122(19): e2424245122 (11 p.) DOI: 10.1073/pnas.2424245122 IF 9.1 (2024)

STAEHR CH., LOGIN H., MELNIKOVA E.V., BAKUN M., ZIEMLIŃSKA E., KISISWA L., ARDESTANI S.B., NOLTE S.S., BECK H.CH., HANSEN BROSTRUP L.M., POSTNOV D., VERKHRATSKY A., MALIK A.R., NYKJAER A., MATCHKOV V.V., SorCS2 is important for astrocytic function in neurovascular signaling. Acta Physiologica (2025) 241(6): e70052 (15 p.) DOI: 10.1111/apha.70052 IF 5.6 (2024)

RYBKA M., MAZUREK Ł., JURAK J., LASKOWSKA A., ZAJDEL M., CZUWARA J., SULEJCZAK D., SZUDZIK M., SAMBOROWSKA E., SCHWARTZ R.A., DZIADEK M., SALAGIERSKI SZ., DRAPAŁA A., UFNAL M., KONOP M. Keratin-TMAO dressing accelerates full-thickness skin wound healing in diabetic rats via M2-macrophage polarization and the activation of PI3K/ AKT/mTOR signaling pathway. International Journal of Biological Macromolecules (2025) 310(3): 143313 (13 p.) DOI: 10.1016/j.ijbiomac.2025.143313 IF 8.5 (2024)

ZAKRZEWSKA-PŁACZEK M., GOLISZ-MOCYDLARZ A., KWAŚNIK A., KRZYSZTOŃ M., NIEDŹWIECKA A., KUFEL J., Defective processing of cytoplasmic and chloroplast ribosomal RNA in the absence of Arabidopsis DXO1. Plant Cell and Environment (2025) 48(6): 4227-4244 DOI: 10.1111/pce.15425 IF 6.3 (2024)

LAX C., MONDO S.J., MARTINEZ J.F., MUSZEWSKA A., BAUMGART L.A., PEREZ-RUIZ J.A., CARILLO-MARIN P., ET AL. Symmetric adenine methylation is an essential DNA modification in the early-diverging fungus Rhizopus microsporus. Nature Communications (2025) 16(1): 3843 (21 p.) DOI: 10.1038/s41467-025-59170-x IF 15.7 (2024)

PAWŁOWSKI P.H., ZIELENKIEWICZ P., Predicting the S. cerevisiae gene expression score by a machine learning classifier. Life-Basel (2025) 15(5): 723 (19 p.) DOI: 10.3390/life15050723 IF 3.4 (2024)

GÓRNIAK D., ŚWIĄTECKI A., KOWALIK J., GRZESIAK J., JASTRZĘBSKI J.P., ZDANOWSKI M.K., High antagonistic activity and antibiotic resistance of flavobacteria of polar microbial freshwater mats on King George Island in maritime Antarctica. Scientific Reports (2025) 15(1): 13615 (15 p.) DOI: 10.1038/s41598-025-97205-x IF 3.9 (2024)

BROUZE M., SZPILA M., CZERWIŃSKA A.M., ANTCZAK W., MROCZEK S., KULIŃSKI T.M., HOJKA-OSIŃSKA A., CYSEWSKI D., GEWARTOWSKA O., ADAMSKA D., GRUCHOTA J., BORSUK E., DZIEMBOWSKI A., DIS3L, cytoplasmic exosome catalytic subunit, is essential for development but not cell viability in mice. RNA (2025) 31(5): 646–662 DOI: 10.1261/rna.080350.124 IF 5.0 (2024)

GORJÃO N., BOROWSKI Ł.S., SZCZĘSNY R.J., GRACZYK D., POLR1D, a shared subunit of RNA polymerase I and III, modulates mTORC1 activity. Biochimica et Biophysica Acta - Molecular Cell Research (2025) 1872(5): 119957 (13 p.) DOI: 10.1016/j.bbamcr.2025.119957 IF 3.7 (2024)

DZIEKOŃSKA A., SZCZEPAŃSKA A., WYSOKIŃSKA A., Effect of season on the characteristics of warmblood stallion spermatozoa stored in a liquid state at 5⁰C. Animals (2025) 15(7): 1035(13 p.) DOI: 10.3390/ani15071035 IF 2.7 (2024)

WIEWIÓRSKA-KRATA N., FORONCEWICZ B., MUCHA K., ZAGOŻDŻON R., Cell therapies for immune-mediated disorders. Frontiers in Medicine (2025) 12: 1550527 (10 p.) DOI: 10.3389/fmed.2025.1550527 IF 3.0 (2024)

DENKIEWICZ-KRUK M., CHAUDHRY D., KRASILIA A., JĘDRYCHOWSKA M., FIJAŁKOWSKA I.J., DMOWSKI M., Effects of CDC45 mutations on DNA replication and genome stability. Biochimica et Biophysica Acta - Molecular Cell Research (2025) 1872 (5): 119936 (14 p.) DOI: 10.1016/j.bbamcr.2025.119936 IF 3.7 (2024)

DĄBROWSKA M., KĘPCZYŃSKA A., GOŹDZIK K., NOWAK N., URAM Ł.,SKONECZNY M., DOLIGALSKA M., SIKORA E., Expression of angiogenic factors in the mammalian senescent cell sustaining Trichinella spp. muscle larvae. Histochemistry and Cell Biology (2025) 163(1): 33 (10 p.) DOI: 10.1007/s00418-025-02363-8 IF 2.1 (2024)

BAZZANI V., KUNDNANI D.L., REDIN M.E., AGOSTINI F., CHHATLANI K., FAINI A.C., POZIEMSKI J., BACCARANI U., SIEDLECKI P., DEAGLIO S., STORICI F., VASCOTTO C., Characterization of a new mutation of mitochondrial ND6 gene in hepatocellular carcinoma and its effects on respiratory complex I. Scientific Reports (2025) 15(1): 10925 (11 p.) DOI: 10.1038/s41598-025-91746-x IF 3.9 (2024)

SOZAŃSKA N., KLEPKA B.P., NIEDŹWIECKA A., ZHUKOVA L., DADLEZ M., GREB-MARKIEWICZ B., OŻYHAR A., TARCZEWSKA A., The molecular properties of the bHLH TCF4 protein as an intrinsically disordered hub transcription factor. Cell Communication and Signaling (2025) 23(1): 154 (20 p.) DOI: 10.1186/s12964-025-02154-7 IF 8.9 (2024)

ALSARRAF M., BANASIAK Ł., TOŁKACZ K., GRZYBEK M., BEHNKE-BOROWCZYK J., ALSARRAF M., DWUŻNIK-SZAREK D., JUŚKO M., AL-QAZAZ D., DRABIK P., BEHNKE J.M., BAJER A., Genetic diversity of Bartonella spp. in rodents and fleas from Poland. Scientific Reports (2025) 15(1): 10710 (21 p.) DOI: 10.1038/s41598-025-92127-0 IF 3.9 (2024)

GRUCA-STRYJAK K., MACIAK K., WINIEWSKA-SZAJEWSKA M., JURKIEWICZ A., GÓRA M., KACPRZAK M.M., DRGAS O., BIAŁEK-PROŚCIŃSKA A., SOBCZYŃSKA-TOMASZEWSKA A., PLUTA K.D., JAMSHEER A., MARKWITZ W., POZNAŃSKI J., BURZYŃSKA B., A novel NEK1 variant disturbs the interaction between the C-terminal fragment of NEK1 and the VDAC1 channel, causing lethal short-rib polydactyly syndrome. Bone (2025) 195: 117471 (11 p.) DOI: 10.1016/j.bone.2025.117471 IF 3.6 (2024)

NIEMCZYK M., WYCZAŁKOWSKA-TOMASIK A., RAKHMETULLINA A., NOWAK MARCIN M., NIEMCZYK S., ZIELENKIEWICZ P., PĄCZEK L., Urinary protein biomarkers as a prognostic tool in autosomal dominant polycystic kidney disease. Journal of Nephrology (2025) 38(2): 803-805 DOI: 10.1007/s40620-025-02205-9 IF 2.6 (2024)

ZANGMO T., SZCZERBA P., KANAVOS I., GUTIÉRREZ-QUINTANILLA A., MIQUEU K., SZPUNAR J., KARAMIANIS P., BAL W., RONGA L., Multinuclear silver(I)−selenium clusters formation in selenopeptides. Inorganic Chemistry (2025) 64(11): 5348−5353 DOI: 10.1021/acs.inorgchem.4c04867 IF 4.7 (2024)

ŻYCHOWSKA M., BAKUŁA Z., DECEWICZ P., HRYNCEWICZ-GWÓŹDŹ A., DYLĄG M., JANKOWSKA-KONSUR A., GAWOR J., GROMADKA R., ŻACZEK A., The Skin mycobiome of patients with atopic dermatitis and healthy volunteers: a case-control study. Experimental Dermatology (2025) 34(3): e70085 (13 p.) DOI: 10.1111/exd.70085 IF 3.1 (2024)

SZCZEPANKOWSKA A.K., CUKROWSKA B., ALEKSANDRZAK-PIEKARCZYK T., Complete genome sequencing and probiotic trait analysis of Lacticaseibacillus rhamnosus LR110, a human stool isolate from the NORDBIOTIC collection. Microbiology Resource Announcements (2025) 14(3): e0111624 (3p.) DOI: 10.1128/mra.01116-24 IF 0.6 (2024)

BLAZIUS B., TROOST J.P., KOPP J.B., PAREKH R.S., GILLESPIE B., AYOUB I., KALLASH M., [...],MUCHA K., ET AL. Clinical decision-making about immunosuppressive treatment in focal segmental glomerulosclerosis. Kidney Medicine (2025) 7(4): 100975 (11p.) DOI: 10.1016/j.xkme.2025.100975 IF 3.4 (2024)

KOPACZ A., KLÓSKA D., BAR A., TARGOSZ-KORECKA M., CYSEWSKI D., AWSIUK K., PIECHOTA-POLAŃCZYK A., CICHOŃ M., CHŁOPICKI S., JÓZKOWICZ A., GROCHOT-PRZĘCZEK A., Endothelial miR-34a deletion guards against aneurysm development despite endothelial dysfunction. Biochimica et Biophysica Acta - Molecular Basis of Disease (2025) 1871: 167812 (16 p.) DOI: 10.1016/j.bbadis.2025.167812 IF 4.2 (2024)

CIEPLAK-ROTOWSKA M.K., DADLEZ M., NIEDŹWIECKA A., Exploring the CNOT1(800–999) HEAT domain and its interactions with Tristetraprolin (TTP) as revealed by hydrogen/deuterium exchange mass spectrometry. Biomolecules (2025) 15(3): 403 (24 p.) DOI: 10.3390/biom15030403 IF 4.8 (2024)

KOMAROWSKA K., FUDALA K., DZIEMBOWSKI M., HAGGE A., BIALIK R., Population status of sympatrically breeding Skuas (Catharacta spp.) at Admiralty Bay, King George Island, Antarctica: A case report for 2020-2024. Biology-Basel (2025) 14(3): 305 (18 p.) DOI: 10.3390/biology14030305 IF 3.5 (2024)

BUGAJEWSKI M., ANGERHOEFER N., PĄCZEK L., KALETA B., Lentinula edodes as a source of bioactive compounds with therapeutical potential in intestinal inflammation and colorectal cancer. International Journal of Molecular Sciences (2025) 26(7): 3320 (24 p.) DOI: 10.3390/ijms26073320 IF 4.9 (2024)