Infrastruktura badawcza

JASCO J-815 Spectropolarimeter
Circular dichroism is a phenomenon based on the differences in the absorption of right- and left-circularly polarized light by a substance. Left- and right-circularly polarized light represent two possible states of photon momentum, which is why circular dichroism is also called spin angular momentum dichroism. Circular dichroism is a manifestation of optical activity. It manifests itself in the absorption bands of optically active chiral molecules.

Spectrofotometer

JASCO's latest research grade spectrofluorometer combines excellent specifications and a flexible optical system with JASCO's unique cross platform spectroscopy software suite Spectra Manager™. The FP-6500 was designed to meet the demanding needs of laboratories involved in application areas like biochemistry performing kinetics, stopped flow, titration and anisotropy experiments. These applications can be easily and rapidly undertaken using dedicated accessories and software.

Spectrofotometer

Varian Cary Eclipse Fluorescence Spectrophotometer
Superior fluorescence sensitivity and fast kinetics.
The Agilent Cary Eclipse Spectrophotometer with unique Xenon flash lamp technology delivers superior sensitivity with fiber optics, high signal-to-noise, and fast kinetic measurement capabilities.
The Varian Cary Eclipse Fluorescence Spectrophotometer is designed for measuring low-volume picomolar fluorescein concentrations (

Spectrofotometer

Microplate reader FLUOstar Omega
Filter-based multi-mode microplate reader
The FLUOstar® Omega is a multi-mode microplate reader with three detection modes. It utilises an ultra-fast UV/vis spectrometer or filters for absorbance as well as highly sensitive filters for all other detection modes. The FLUOstar Omega is the ideal plate reader for life science applications.
Features
High-speed absorbance measurements
Measurements in up to 384-well plates
Top and bottom reading
Incubation up to 45

Multiplate Reader

AA500 Atomic Absorption
The instrument is available with a flame atomiser and graphite furnace. Three flame options are available namely – Air/Acetylene, N2O/Acetylene and Air/LPG (Natural gas). The system can be fully automated via either our Universal Auto-sampler OR a Random Access Auto-sampler. Hydride analyse is also available can also be FULLY automated. The instrument is FULLY controlled via our ‘user-friendly’ software AAWin. With more than 1000 units sold World Wide the AA500 is used i

Spectrofotometer

The Liberty Blue™ automated microwave peptide synthesizer features a 4-minute cycle time along with a 90% solvent reduction, based
on High Efficiency Solid Phase Peptide Synthesis (HE-SPPS), developed in 2013 and CarboMAX™ methodology, developed in 2018. This
system is utilized in hundreds of laboratories worldwide and provides unparalleled peptide quality, based on its unique methodology and
use of microwave energy. The Liberty Blue features the latest in engineering for fluidic deliveries, tru

Others

Elevated Temperature Cleavage
Razor
Overview
With the advantages of precision heated reactions, you can get better peptide purity. Now you can cleave up to 12 peptides, simultaneously, in 30 minutes or less, with more reliability than any other method. This is high throughput cleavage. Fast: Cleave as quickly as you purify.
Microcleavage in as little as 2 minutes provides mass spectrometry level confidence that expensive amino acids and scale-up syntheses are coupled completely.

Others

Automated Parallel Peptide Synthesizer
MultiPep 1
Overview
The MultiPep 1TM is a highly flexible and economical automated parallel peptide synthesizer. It features unmatched flexibility for screening hundreds of peptides in parallel using plates, columns, or cellulose membranes formats.
Flexible Formats
Plate = up to 96 peptides at 1-10 μmol
Columns = up to 48 peptides at 1-10 μmol or 8 peptides at 10-300 μmol
SPOT Synthesis = up to 1200 peptides on two cellulose membranes
CelluSpots™ = up to 76

Others

Anaerobic chamber intended only for chemical research. Only oxygen sensor (there is no carbon dioxide sensor). Coy Anaerobic Chambers eliminate oxygen to 0-5 parts per million (ppm) using a hydrogen gas mix (5% or less) reacting with a palladium catalyst to remove oxygen by forming a water molecule. A vacuum airlock is used to reduce oxygen levels prior to transfer of samples and tools in and out of the glove box.

Others

Two blocks – gradient-enabled dual 48/48 fast – recommended sample volume 10-50 ul (50 ul limit);
Sample capacity – 2 x 48 x 0.2 ml tubes;
Maximum ramp rate 4°C/sec;
Average ramp rate 3°C/sec;
Temperature range 0–100°C;
Temperature accuracy ±0.2°C of programmed target at 90°C;
Temperature uniformity ±0.4°C well-to-well within 10 sec of arrival at 90°C;
Gradient capability Yes – Gradient range 30–100°C
Temperature differential range 1–24°

PCR/qPCR/ddPCR

temperature -9 °C to +40 °C;
Rotor: S-4-72 – swing-bucket rotor with 4×250 ml round buckets;
max speed 4200 rpm;
max load per bucket 450 g.
Adapters:
for 8 conical tubes 15 mL (max.  17 mm), set of 4 pieces;
for 4 conical tubes 50 mL (max.  30 mm), set of 4 pieces;
Mixed loading of swing-bucket rotors is possible. Buckets or plates buckets that are located opposite each other must be of the same type.

Centrifugation

temperature +2 °C to +35 °C;
max Speed n max 15200 rpm (depending on the rotor);
min Speed n min 300 rpm;
maximum RCF value at n max 25314 x g
Rotors:
FIBERLiteTM F14S-6 x 250 LE
FIBERLiteTM F15-8 x 50cy
M-20
The user-friendly control panel makes it easy to pre-set the speed, RCF value, running time,
temperature, and running profile. You can choose between the display of speed and RCF or the entry mode. These settings can be changed even while the centrifuge is running.

Centrifugation

UV-1800 Spectrophotometer Shimadzu UV-VIS
Photometric system – Double beam optics
Monochromator – Blazed holographic grating in Czerny-Turner mounting
Wavelength range – 190 to 1,100nm
Spectral bandwidth – 1 nm (190 to 1,100 nm)
Detector – Silicon photodiode
Output device – USB flash drive (optional)
Multicell Sample Compartment (Six Cells)
Holds up to six 10 mm square cells. No temperature control capability.
Cell switching is automatic.
Number of cells: 6 on the sample side; 1 on the refere

Spectrofotometer

Urządzenie do analizy ilościowej i jakościowej cukrów prostych obojętnych, heksozoamin, kwasu sialowego, aminokwasów.
Cukry są rozdzielane na kolumnie CarboPacPA10 a detekcja jest przeprowadzana za pomocą impulsowej detekcji amperometrycznej (PAD)
Po odpowiedniej obróbce można oznaczać cukry ściany komórkowej grzybów, cukry związane z białkami itp.

HPLC/FPLC

A precise instrument for studying biomolecular interactions by directly measuring binding thermodynamics. It provides key parameters such as affinity, stoichiometry, enthalpy, and entropy of interactions. The SVH version offers high sensitivity and precise temperature control, supporting a wide range of applications from protein – ligand binding to nucleic acid complex formation.

Others

A highly sensitive calorimeter for analyzing thermal stability of biomolecules. It measures heat absorbed or released during heating and cooling, providing insights into unfolding, melting, and conformational changes of proteins, nucleic acids, and biotherapeutics. Enables determination of enthalpy, entropy, and free energy, using small sample volumes in a non-destructive way.

Others, Others

Used to determine the size and distribution of particles in solution, including proteins, nanoparticles, and macromolecules. It covers a wide range (0.5 nm–2.5 µm) with high sensitivity and robustness. The instrument requires only minimal sample volumes and can be optionally equipped with static light scattering for molecular weight determination.

Others

Used to determine the size and distribution of particles in solution, including proteins, nanoparticles, and macromolecules. It covers a wide range (0.5 nm–2.5 µm) with high sensitivity and robustness. The instrument requires only minimal sample volumes and can be optionally equipped with static light scattering for molecular weight determination.

Others

A high-precision nanoDSF instrument for label-free analysis of protein stability. It monitors intrinsic fluorescence changes upon thermal or chemical unfolding, providing melting points (Tm), aggregation data, and stability profiles. Up to 48 samples can be analyzed simultaneously, making it ideal for protein characterization and drug discovery studies.

Isothermal Electrophoresis

1) Pipette adapter: accommodates all INTEGRA electronic multichannel pipettes – with fixed and adjustable tip spacing – and the D-ONE single channel pipetting module.
2) User Interface: program setup and selection is done using the pipette’s intuitive user interface.
3) Deck: up to four work positions are available to accommodate reagent reservoirs, tube racks and plates.
4 & 5) Automatic tip change: two dedicated positions for automatic tip loading and ejection.

Automatic Liquid Handling