Laboratories

Our laboratory is interested in identifying cellular mechanisms and pharmacological interventions that contribute to the maintenance of protein homeostasis during acute cellular stress and aging. (…)

Regulation of mRNA transcription and co-transcriptional events along with degradation are key for adjusting gene expression in response to stimuli. One line of our research aims to describe regulation of (…)

A new proteostasis mechanism for the removal of protein aggregates and damaged mitochondria has recently been described. Within this process, cellular waste material is ejected from the cell via large (…)

We are interested in understanding how the biophysics of transcription affects gene regulation. Our goal is to apply this knowledge to problems such as SARS-CoV-2 transcription and RNA polymerase III‑related (…)