Research projects

NATIONAL SCIENCE CENTRE

HARMONIA

  • Title: The CMGE helicase-polimerase complex a factor integrating the regulation of cell cyle progression and DNA replication
    Project leader: Dr Michał Dmowski
    Duration: 2018-05-18 / 2022-05-17
    Budget: 1 288 000 PLN
  • Title: The platform based on nanobody (VHH) against SWI/SNF-type chromatin remodeling complex subunits as the innovative tool for precisely controlled complex innactivation and molecular biology studies
    Project leader: Dr hab. Tomasz Sarnowski
    Duration: 2019-07-26 / 2022-07-25
    Budget: 1 499 400 PLN

MINIATURA

  • Title: Species diversity of gastrointestinal parasites of the Antarctic fur seal (Arctocephalus gazella)
    Project leader: Dr Katarzyna Tołkacz
    Duration: 2021-12-15 / 2022-12-14
    Budget: 49 995 PLN
  • Title: Identification of new proteins involved in DNA segregation and condensation in Pseudomonas aeruginosa using transposon insertion sequencing (Tn-seq)
    Project leader: Dr Adam Kawałek
    Duration: 2021-12-15 / 2022-12-14
    Budget: 49 500 PLN
  • Title: Effects of the selected biochars on dark fermentation: efficiency of hydrogen production from sugar beet molasses and stability of microbial communities in continuous system
    Project leader: Dr inż. Anna Detman
    Duration: 2021-12-02 / 2022-12-01
    Budget: 49 896 PLN

OPUS

  • Title:  Changes in transcriptomic and proteomic profiles and life history parameters of Daphnia in the response to alkylating agents contaminating environment
    Project leader: Prof. dr hab. Elżbieta Grzesiuk
    Duration: 2017-01-12 / 221-02-11
    Budget: 1 059 740 PLN
  • Title: Study of the role and biosynthesis of bacterial-like polyprenols in eukaryoticyc cells
    Project leader: Dr Liliana Surmacz
    Duration: 2017-01-24 / 2022-01-23
    Budget: 900 000 PLN
  • Title:  Interplay of posttranslational redox cysteine modifications and metal ion binding as key to conformational and functional plasticity of innate immunity and cancer biomarkers – S100A8 and S100A9 proteins
    Project leader: Dr Aleksandra Wysłouch-Cieszyńska
    Duration: 2016-03-01 / 2022-09-01
    Budget: 1 033 600 PLN
  • Title: Understanding of the functioning of mitochondrial ATP synthase by studying in yeast the phenotype of human pathology related mutations in the mitochondrial DNA.
    Project leader: Dr hab. Róża Kucharczyk
    Duration: 2017-07-25 / 2022-07-04
    Budget: 1 061 800 PLN
  • Title:  The role of SnRK2 kinases in regulation of pre-mRNA alternative splicing and miRNA biogenesis in plants response to salinity
    Project leader: Prof. dr hab. Grażyna Dobrowolska
    Duration: 2017-09-28 / 2022-09-27
    Budget: 1 631 250 PLN
  • Title: How activation of the Mec1/Tel1 kinase (human ATR/ATM) pathway in response to the nuclear genome damage influences the stability of mitochindrial genome: a study on the yeast model of mutations in polymerase POLG
    Project leader: Dr hab. Aneta Kaniak-Golik
    Duration: 2018-01-09 / 2023-01-08
    Budget: 818 000 PLN
  • Title: The role of Rbs1 protein in control of general response to defect in tRNA biosynthesis in yeast Saccharomyces cerevisiae
    Project leader: Prof. dr hab. Magdalena Rakowska-Boguta
    Duration: 2018-01-10 / 2022-01-09
    Budget: 957 600 PLN
  • Title: Thermodynamics of halogen bonding in the bio-molecular cage
    Project leader: Prof. dr hab. Jarosław Poznański
    Duration: 2018-01-15 / 2022-10-14
    Budget: 1 398 000 PLN
  • Title: Analysis of selected processes influencing the architecture of fungal genomes and proteomes
    Project leader: Dr hab. Anna Muszewska
    Duration: 2018-01-19 / 2022-01-18
    Budget: 403 840 PLN
  • Title: The role of ALKBH proteins in obesity and type 2 diabetes development using the pig model
    Project leader: Prof. dr hab. Elżbieta Grzesiuk
    Duration: 2019-01-19 / 2022-01-17
    Budget: 1 240 920 PLN
  • Title: Quantitative assessment of sediment transport from glaciers of South Shetland Islands on the basis of selected remote sensing methods
    Project leader: Dr hab. Robert Bialik
    Duration: 2018-07-02 / 2022-07-01
    Budget: 898 400 PLN
  • Title: Variability of Antarctic lichen microbiome in a trophic and a spatio-temporal gradient (King George Island, South Shetland Islands)
    Project leader: Dr Jakub Grzesiak
    Duration: 2018-05-21 / 2022-05-20
    Budget: 817 020 PLN
  • Title: Apoptotic machinery: An ancient adaptation to aerobic conditions?
    Project leader: Dr hab. Szymon Kaczanowski
    Duration: 2018-06-29 / 2022-12-28
    Budget: 786 200 PLN
  • Title: SnRK2 protein kinases as integrators of environmental signals in the regulation of the senescence in plants
    Project leader: Dr Anna Marta Kulik
    Duration: 2018-10-31 / 2022-10-30
    Budget: 1 552 100 PLN
  • Title: Isolation of resistance genes to PVY infection, usefull in potato (Solanum tuberosum L) breading and its functional analysis
    Project leader: Prof. dr hab. Jacek Hennig
    Duration: 2018-07-20 / 2022-07-19
    Budget: 1 457 500 PLN
  • Title: Clonal analysis of Streptococcus pyogenes strains resistant to macrolide antibiotics
    Project leader: Dr Izabela Kern-Zdanowicz
    Duration: 2018-08-14 / 2021-08-13
    Budget: 1 027 302 PLN
  • Title: Integrating light and osmotic stress signaling- molecular functions of Plastid Movement Impaired 1 protein from Arabidopsis thaliana
    Project leader: Mgr Olga Sztatelman
    Duration: 2019-01-14 / 2023-01-13
    Budget: 1 242 600 PLN
  • Title: Dolichol – a superlipid essential for the functioning of the eukaryotic cell
    Project leader: Prof. dr hab. Ewa Kula-Świeżewska
    Duration: 2019-01-14 / 2023-01-13
    Budget: 1 997 400 PLN
  • Title: The role and cooperation of AidB dehydrogenase and AlkB dioxygenase in repair of adducts to DNA and RNA bases
    Project leader: Dr hab. Agnieszka Maciejewska
    Duration: 2019-01-09 / 2023-01-08
    Budget: 924 400 PLN
  • Title: Analysis of functional interdependence between organ-specific choice of alternative transcription start site (altTSS) and SWI/SNF dependent chromatin remodeling in Arabidopsis
    Project leader: Dr Szymon Kubala
    Duration: 2019-01-14 / 2023-01-13
    Budget: 1 618 800 PLN
  • Title: Novel molecular mechanisms in extracellular copper transport
    Project leader: Prof. dr hab. Wojciech Bal
    Duration: 2019-01-15 / 2023-01-14
    Budget: 1 522 000 PLN
  • Title: Characterization of genetic determinants of propionic acid biosynthesis and assessing of their functionality in selected lactic acid bacteria
    Project leader: Dr hab. Tamara Aleksandrzak-Piekarczyk
    Duration: 2019-01-09 / 2023-01-08
    Budget: 623 000 PLN
  • Title: Topology of Pseudomonas aeruginosa chromosome. The role of partitioning protein ParB
    Project leader: Prof. d hab. Grażyna Jagura-Burdzy
    Duration: 2019-02-15 / 2023-02-14
    Budget: 2 100 800 PLN
  • Title: A proteomic approach to define interactors of Zika Virus with the host cell nucleolus
    Project leader: Prof. dr hab. Michał Dadlez
    Duration: 2019-01-24 / 2023-01-23
    Budget: 1 072 126 PLN
  • Title: Regulation of cell death and OXPHOS activity by Fmp40 ampylase in yeast S. cerevisiae
    Project leader: Dr hab. Róża Kucharczyk
    Duration: 2019-06-13 / 2022-06-12
    Budget: 1 671 600 PLN
  • Title: The role of HopAG1 effector in virulence of plant pathogenic bacteria
    Project leader: Dr Magdalena Górecka
    Duration: 2019-06-18 / 2022-06-17
    Budget: 1 021 800 PLN
  • Title: Design of photoswitchable dismantlers of biomaterials made of amyloid fibrils
    Project leader: Dr Dorota Niedziałek
    Duration: 2019-06-18 / 2022-06-17
    Budget: 618 600 PLN
  • Tytuł projektu: Uncovering novel secondary seed dormancy regulators in Arabidopsis
    Project leader: Dr Ruslan Yatusewich
    Duration: 2019-06-18 / 2022-06-17
    Budget: 1 456 400 PLN
  • Title: Characterisation of function and substrate binding of the prefoldin chaperone in physiology and cellular stress
    Project leader: Dr Ulrike Topf
    Duration: 2019-10-01 / 2022-09-30
    Budget: 1 882 500 PLN
  • Title: Identification of Streptococcus aninosus virulence factors
    Project leader: Dr hab. Izabela Kern-Zdanowicz
    Duration: 2019-09-02 / 2022-09-01
    Budget: 1 005 620 PLN
  • Title: Modification and action of non-coding RNA
    Project leader: Dr Jacek Nowak
    Duration: 2020-02-05 / 2023-02-04
    Budget: 2 063 140 PLN
  • Title: Functional genomic analysis of Staphylococcus aureus Kayvirus genus phages in a search for molecular basis of wide host-range and the strategies of survival with a host population
    Project leader: Dr hab. Małgorzata Barbara Łobocka
    Duration: 2020-02-06 / 2023-02-05
    Budget: 2 249 194 PLN
  • Title: New aspects of negative regulation of RNA polymerase III in yeast Saccharomyces cerevisiae
    Project leader: Dr Małgorzata Maria Cieśla
    Duration: 2020-09-01 / 2023-08-31
    Budget: 1 252 200 PLN
  • Title: Identification and comprehensive classification of peptidases
    Project leader: Dr Kamil Steczkiewicz
    Duration: 2020-06-25 / 2023-06-24
    Budget: 878 400 PLN
  • Title: Novel mechanisms regulating the activity of cis-prenyltransferases in plants
    Project leader: Dr hab. Liliana Surmacz
    Duration: 2020-10-02 / 2024-10-01
    Budget: 1 969 800 PLN
  • Title: In solution or in the membrane? Determination of partition of beta-amyloid peptides between the water and phospholipid phase and its small molecular effectors
    Project leader: Prof. dr hab. Wojciech Bal
    Duration: 2021-01-19 / 2024-01-18
    Budget: 2 269 200 PLN
  • Title: Novel aspects of virulence mechanisms of HopBF1, a bacterial effector that targets host HSP90 protein
    Project leader: Dr hab. Magdalena Krzymowska
    Duration: 2021-03-15 / 2025-03-14
    Budget: 2 131 200 PLN
  • Title: Assessing protein-ligand complexes with ML/DL models trained on molecular dynamics-based descriptors
    Project leader: Dr hab. Paweł Aleksander Siedlecki
    Duration: 2021-07-16 / 2024-07-15
    Budget: 517 280 PLN
  • Title: Identification of the interdependence between SWI/SNF-type chromatin remodeling complex, metabolism control and RNA modification in salivary gland cystic carcinoma as a basis for a new targeted therapy
    Project leader: Dr hab. Tomasz Jacek Sarnowski
    Duration: 2021-07-23 / 2025-07-22
    Budget: 2 532 720 PLN
  • Title: Interferon-inducible anti-bacterial immunity factors of the host cell cytosol
    Project leader: Dr Michał Piotr Wandel
    Duration: 2021-09-01 / 2025-08-31
    Budget: 2 586 000 PLN
  • Title: LCRPlatform: new algorithms and methods for the comprehensive identification, categorization, and annotation of protein low complexity regions
    Project leader: Dr hab. Marcin Maciej Grynberg
    Duration: 2021-03-15 / 2025-03-14
    Budget: 464 820 PLN
  • Title: The role of alternative EF-G’s in translation regulation during antibiotic biosynthesis in Myxococcus xanthus
    Project leader: Dr hab. Agata Lucyna Starosta
    Duration: 2021-10-29 / 2025-10-28
    Budget: 3 513 000 PLN
  • Title: Ancestral traits and genomic innovations in early diverging fungi – implications for mucormycosis
    Project leader: Dr hab. inż. Anna Muszewska
    Duration: 2022-03-01 /
    Budget: 1 348 588 PLN
  • Title: Molecular basis of neurodegenerative diseases – the influence of selected metallic nanoparticles
    Project leader: Prof. dr hab. Maciej Leszek Kozak / Dr Igor Żukow
    Duration: 2021-12-23 / 2025-12-22
    Budget: 366 000 PLN
  • Title: Impact of Lactococcus and Leuconostoc bacteria on reinforcing gut barrier – from identification of potentially probiotic strains and molecular factors involved in muco-affinity to evaluation of their mucus protective function in vivo
    Project leader: Dr hab. Magdalena Kowalczyk
    Duration: 2022-03-01 /
    Budget: 1 558 126 PLN
  • Title: Mechanisms regulating the cellular level of the most mutagenic human DNA polymerase – the role of p300 acetyltransferase and hypoxia
    Project leader: Dr hab. Justyna McIntyre
    Duration: 2022-01-12 / 2026-01-11
    Budget: 1 763 200 PLN
  • Title: Posttranscriptional reshaping of mRNA pool in seeds
    Project leader: Dr Michał Adam Krzysztoń
    Duration: 2022-03-01 /
    Budget: 1 817 800 PLN
  • Title: Expanding the mitochondrial proteome via the non-canonical translation mechanisms
    Project leader: Prof. dr hab. Joanna Kufel/ Dr hab. Roman Szczęsny
    Duration: 2022-09-01 /
    Budget: 1 596 000 PLN

PRELUDIUM

  • Title: The role of the Cdc45 protein in the maintenance of genomic stability in yeast Saccharomyces cerevisiae
    Project leader: Mgr Milena Denkiewicz-Kruk
    Duration: 2017-06-02 / 2023-03-01
    Budget: 150 000 PLN
  • Title: Identification of nuclear function of Arabidopsis Target of Rapamycin protein
    Project leader: Mgr Paweł Ćwiek
    Duration: 2018-01-25 / 2021-01-24
    Budget: 180 000 PLN
  • Title: Characterization of genetic determinants of the mannose-specific phosphotransferase system (Man-PTS) determining sensitivity to the newly identified subclass IId bacteriocins
    Project leader: Mgr Aleksandra Tymoszewska
    Duration: 2019-01-09 / 2022-08-08
    Budget: 139 800 PLN
  • Title: Evaluation of the function of the SNF5-type core sibunit of the SWI/SNF complex on Arabidopsis thaliana using new T-DNA insertionan knock-out line
    Project leader: Mgr Jarosław Steciuk
    Duration: 2019-01-15 / 2023-01-14
    Budget: 210 000 PLN
  • Title: The PA2504 protein – a novel player in regulation of exotoxin A production of Pseudomonas aeruginosa?
    Project leader: Mgr Joanna Drabińska
    Duration: 2019-01-24 / 2022-01-23
    Budget: 138 720 PLN
  • Title: Biology and systematics of Antarctic polar lactic acid bacteria strains of the genus Carnobacterium in the light of phenotypic and genetic analyses
    Project leader: Mgr inż. Katarzyna Kosiorek
    Duration: 2019-06-21 / 2022-06-20
    Budget: 139 980 PLN
  • Title: Identification of group I SnRK2s substrates involved in RNA metabolism and elucidation the role of their phosphorylation
    Project leader: Mgr Adrian Kasztelan
    Duration: 2020-02-28 / 2023-02-27
    Budget: 210 000 PLN
  • Title: Moonlighting role of yeast WASP (Las17) in the nucleolus: possible implications for Wiskott-Aldrich syndrome etiology
    Project leader: Mgr Justyna Antoniuk-Majchrzak
    Duration: 2020-02-05 / 2023-02-04
    Budget: 203 544 PLN
  • Title: Analysis of Escherichia coli ydiU mutation suppressors and detergent resistant membrane fraction as a way to discover functional relationships of family SelO AMPylases involved in oxidative stress response from bacteria to humans
    Project leader: Mgr Monika Karasiewicz-Urbańska
    Duration: 2020-06-15 / 2022-06-14
    Budget: 139 656 PLN
  • Title: Analysis of bacteriophage P1 lytic functions as a way to discover the mechanisms of wide dissemination of clinical bacterial strains carrying P1 derivatives with genes encoding resistance to new generation beta-lactam antibiotics
    Project leader: Mgr Agnieszka Bednarek
    Duration: 2020-06-25 / 2023-06-24
    Budget: 139 920 PLN
  • Title: Differential activity of ribonucleotide repair on leading and lagging DNA strand and its consequences for the mechanism and fidelity of replication of both DNA strands in Escherichia coli cells
    Project leader: Mgr Krystian Łazowski
    Duration: 2020-07-28 / 2022-07-27
    Budget: 139 920 PLN
  • Title: The role of NBR1 and the LSU (RESPONSE TO LOW SULFUR) proteins in stability of Arabidopsis thaliana catalases
    Project leader: Mgr inż. Anna Niemiro
    Duration: 2022-01-12 / 2023-01-11
    Budget: 69 540 PLN

PRELUDIUM BIS

  • Title: High-resolution analysis of data from proton-deuterium exchange experiments monitored by mass spectrometry
    Project leader: Prof. dr hab. Michał Dadlez
    Duration: 2020-10-01 / 2024-09-30
    Budget: 519 600 PLN

SONATA

  • Title: Rab-dependent vesicular transport and sterol homeostasis- where is the link?
    Project leader: Dr Małgorzata Gutkowska-Stronkowska
    Duration: 2017.02.07 / 2021-02-06
    Budget: 432 800 PLN
  • Title: Mechanisms of polyprenol biosynthesis regulation at transcriptional level
    Project leader: Dr Daniel Buszewicz
    Duration: 2018-04-20 / 2021-04-19
    Budget: 990 000 PLN
  • Title: Comprehensive study of the role of Rysto, a TIR-NB-LRR class receptor in potato innate immunity
    Project leader: Dr Marta Grech-Baran
    Duration: 2020-06-25 / 2023-06-24
    Budget: 909 000 PLN
  • Title: Molecular mechanisms driving formation of muscular exophers and their role in proteostasis and life cycle of C. elegans
    Project leader: Dr Michał Turek
    Duration: 2020-11-05 / 2023-11-04
    Budget: 1 896 240 PLN
  • Title: Molecular mechanisms linking RNA polymerase III mutations to Hypomyelinating leukodystrophy (HLD)
    Project leader: Dr Tomasz Wojciech Turowski
    Duration: 2021-07-16 / 2024-07-15
    Budget: 1 535 600 PLN
  • Title: Nowy mechanizm kontroli ekspresji genów u Eukaryota poprzez regulację długości ogonów poliadenozynowych kodujących transkryptów
    Project leader: Dr Agnieszka Irena Tudek
    Duration: 2021-10-01 / 2024-09-30
    Budget: 1 642 400 PLN

SONATA BIS

  • Title: Dissection of putative transcriptional regulators from Pseudomonas aeruginosa proteome dependent on ParA/ParB using systems biology tools
    Project leader: Dr hab. Aneta Bartosik
    Duration: 2016.04.20 / 2022-04-19
    Budget: 1 518 680 PLN
  • Title: Analysis of the human SKI complex, a central player in cytoplasmic RNA decay and surveillance pathways
    Project leader: Dr hab. Rafał Tomecki
    Duration: 2018-05-08 / 2023-05-07
    Budget: 2 643 200 PLN
  • Title: Bet-hedging in plants – multi level analysis of seed dormancy variability – from singel cell to population
    Project leader: Dr hab. Szymon Świeżewski
    Duration: 2019-06-13 / 2024-06-12
    Budget: 3 711 000 PLN
  • Title: How does ribosome heterogeneity contribute to cellular stress defense?
    Project leader: Dr Ulrike Topf
    Duration: 2020-10-01 / 2025-09-30
    Budget: 3 861 212 zł

SONATINA

  • Title: Polyhydroxyacids of psychrophilic polar region bacteria: role in bacterial adaptation to stress conditions and biotechnological potential
    Project leader: Dr Jakub Grzesiak
    Duration: 2017-10-10 / 2022-04-09
    Budget: 647 116 PLN
  • Title: Transport pathway for non-coding RNA during meiosis
    Project leader: Dr Julita Gruchota
    Duration: 2019-09-12 / 2022-09-11
    Budget: 999 465 PLN

SHENG

  • Title: Dissecting DNA Maintenance Methylation in Mammals: Fidelity, Timing and Instructive Cues
    Project leader: Prof. dr hab. Matthias Bochtler
    Duration: 2019-10-02 / 2023-10-01
    Budget: 1 737 600 PLN

BEETHOVEN LIFE

  • Title: Dissection of the signaling function of O-acetylserine in plants
    Project leader: Prof. dr hab. Agnieszka Ewa Sirko
    Duration: 2020-01-29 / 2023-01-28
    Budget: 1 472 600 PLN

THE POLISH NATIONAL AGENCY FOR ACADEMIC EXCHANGE

INTERNATIONAL COOPERATION AND EXCHANGE

  • Title: Mass spectrometry imaging of single seeds in relation with seed physiological quality
    Project leader: Dr hab. Szymon Świeżewski
    Duration:
    Budget: 25 000 PLN

POLISH RETURNS

  • Title: Identification and characterisation of novel anti-bacterial restriction factors Project leader: Dr Michał Wandel
    Duration: 2021-09-01 / 2025-09-01
    Budget: 1 780 000 PLN
  • Title: Functional framework for viral RNA-dependent RNA polymerase, a major target in COVID19 treatment
    Project leader: dr Tomasz Turowski
    Duration: 2021-08-01 / 2025-07-31
    Budget: 1 760 000 PLN

WELCOME

  • Title: Welcome to IBB
    Project leader: Dr hab Roman Szczęsny
    Duration: 2021-06-01 / 2023-05-31
    Budget: 316 260 PLN

NATIONAL CENTRE FOR RESEARCH AND DEVELOPMENT

  • Title: Application of novel diagnostic and therapeutical methods in epilepsy and neurodevelopmental abnormalities in children based on the clinical and cellular model of mTOR dependent epilepsy
    Project leader: Prof. dr hab. Michał Dadlez
    Duration: 2017-04-01 / 2021-09-30
    Budget: 3 928 980 zł

MEDICAL RESEARCH AGENCY

EMBO

  • Title: Translation regulation in bacteria – Specialized ribosomes in Bacillus subtilis.
    Project leader: Dr hab. Agata Starosta
    Duration: 2021-04-01 / 2022-12-31
    Budget: 639 425 PLN
  • Title: Intracellular mechanisms of anti-microbial immunity
    Project leader: Dr Michał Wandel
    Okres realizacji: 2021-09-01 / 2021-08-30
    Budget: 705 000 PLN

HORIZON

MCSA – European Postdoctoral Fellowships

  • Title: Population-wide analysis of molecular and metabolic features intrinsic to dormancy variability in single seeds — POP1Seed
    Project leader: Dr Julia Zinsmeister
    Duration: 2021-10-01 / 2024-09-30
    Budget: 623 788 PLN