Scientists from IBB PAS have described a new mechanism for the regulation of extracellular vesicles formation

Members of the Laboratory of Animal Molecular Physiology, led by Michał Turek, in collaboration with Wojciech Pokrzywa and his team from IIMCB, have described a mechanism for regulating the formation of extracellular vesicles (exophers) in a model organism, the nematode Caenorhabditis elegans. The authors of the study described how individual cells of the nervous system control the production of exophers in response to substances secreted by other individuals in the population. The relationship between the olfactory system and the production of extracellular vesicles suggests the existence of new mechanisms for regulating cellular processes based on olfactory signals from the environment. The occurrence of similar mechanisms in other species may have significant implications for understanding the impact of the evolution and adaptation of social behaviour on the intracellular processes of organisms. The research findings were published in the prestigious journal Nature Communications.

The work was supported by the National Science Centre (SONATA and SONATA BIS grants for MT, GRIEG grant for WP) and the Foundation for Polish Science (FIRST TEAM grant for WP).

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